Showing posts with label White. Show all posts
Showing posts with label White. Show all posts

Tuesday, 22 November 2011

High-quality white light produced by four-color laser source; Diode lasers could challenge LEDs for home and industrial lighting supremacy

ScienceDaily (Oct. 26, 2011) — The human eye is as comfortable with white light generated by diode lasers as with that produced by increasingly popular light-emitting diodes (LEDs), according to tests conceived at Sandia National Laboratories.

Both technologies pass electrical current through material to generate light, but the simpler LED emits lights only through spontaneous emission. Diode lasers bounce light back and forth internally before releasing it.

The finding is important because LEDs -- widely accepted as more efficient and hardier replacements for century-old tungsten incandescent bulb technology -- lose efficiency at electrical currents above 0.5 amps. However, the efficiency of a sister technology -- the diode laser -- improves at higher currents, providing even more light than LEDs at higher amperages.

"What we showed is that diode lasers are a worthy path to pursue for lighting," said Sandia researcher Jeff Tsao, who proposed the comparative experiment. "Before these tests, our research in this direction was stopped before it could get started. The typical response was, 'Are you kidding? The color rendering quality of white light produced by diode lasers would be terrible.' So finally it seemed like, in order to go further, one really had to answer this very basic question first."

Little research had been done on diode lasers for lighting because of a widespread assumption that human eyes would find laser-based white light unpleasant. It would comprise four extremely narrow-band wavelengths -- blue, red, green, and yellow -- and would be very different from sunlight, for example, which blends a wide spectrum of wavelengths with no gaps in between. Diode laser light is also ten times narrower than that emitted by LEDs.

The tests -- a kind of high-tech market research -- took place at the University of New Mexico's Center for High Technology Materials. Forty volunteers were seated, one by one, before two near-identical scenes of fruit in bowls, housed in adjacent chambers. Each bowl was randomly illuminated by warm, cool, or neutral white LEDs, by a tungsten-filament incandescent light bulb, or by a combination of four lasers (blue, red, green, yellow) tuned so their combination produced a white light.

The experiment proceeded like an optometrist's exam: the subjects were asked: Do you prefer the left picture, or the right? All right, how about now?

The viewers were not told which source provided the illumination. They were instructed merely to choose the lit scene with which they felt most comfortable. The pairs were presented in random order to ensure that neither sequence nor tester preconceptions played roles in subject choices, but only the lighting itself. The computer program was written, and the set created, by Alexander Neumann, a UNM doctoral student of CHTM director Steve Brueck.

Each participant, selected from a variety of age groups, was asked to choose 80 times between the two changing alternatives, a procedure that took ten to twenty minutes, said Sandia scientist Jonathan Wierer, who helped plan, calibrate and execute the experiments. Five results were excluded when the participants proved to be color-blind. The result was that there was a statistically significant preference for the diode-laser-based white light over the warm and cool LED-based white light, Wierer said, but no statistically significant preference between the diode-laser-based and either the neutral LED-based or incandescent white light.

The results probably won't start a California gold rush of lighting fabricators into diode lasers, said Tsao, but they may open a formerly ignored line of research. Diode lasers are slightly more expensive to fabricate than LEDs because their substrates must have fewer defects than those used for LEDs. Still, he said, such substrates are likely to become more available in the future because they improve LED performance as well.

Also, while blue diode lasers have good enough performance that the automaker BMW is planning their use in its vehicles' next-generation white headlights, performance of red diode lasers is not as good, and yellow and green have a ways to go before they are efficient enough for commercial lighting opportunities.

Still, says Tsao, a competition wouldn't have to be all or nothing. Instead, he said, a cooperative approach might use blue and red diode lasers with yellow and green LEDs. Or blue diode lasers could be used to illuminate phosphors -- the technique currently used by fluorescent lights and the current generation of LED-based white light -- to create desirable shades of light.

The result makes possible still further efficiencies for the multibillion dollar lighting industry. The so-called ''smart beams'' can be adjusted on site for personalized color renderings for health reasons and, because they are directional, also can provide illumination precisely where it's wanted.

Colorimetric and experimental guidance was provided by the National Institute of Standards and Technology.

The research was published in the July 1 issue of Optics Express.

This work was conducted as part of the Solid-State Lighting Science Energy Frontier Research Center, funded by the U.S. DOE Office of Science.

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Story Source:

The above story is reprinted from materials provided by DOE/Sandia National Laboratories.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

A. Neumann, J. J. Wierer, W. Davis, Y. Ohno, S. R. J. Brueck, J.Y. Tsao. Four-color laser white illuminant demonstrating high color-rendering quality. Optics Express, 2011; 19 (S4): A982 DOI: 10.1364/OE.19.00A982

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.


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Sunday, 8 May 2011

White matter disease: Genetic mutation causing MLC identified

ScienceDaily (May 4, 2011) — White matter disease (WMD) covers a large group of disorders that affect the white matter, or myelin. In children these disorders are commonly genetic and often go undiagnosed. In new research, a team led by Raúl Estévez, a lecturer from the Department of Physiological Sciences II, based at the UB's Bellvitge Health Sciences Campus, working with the researcher Marjo van der Knaap, from the University Medical Centre at VU University Amsterdam, have identified mutant GlialCAM as responsible for 25% of cases of megalencephalic leukoencephalopathy with subcortical cysts (MLC), a rare genetic disease affecting cerebral myelin.

Also participating in the study, which has been published and selected as a featured article in The American Journal of Human Genetics, were Tania López-Hernández, co-principal author and a postdoctoral fellow at the UB, and the researchers Albert Martínez, from the Institute of Biomedical Research (IRB Barcelona), and Virginia Nunes, a lecturer at the UB and researcher for the Bellvitge Biomedical Research Institute (IDIBELL).

Myelin is required for the correct propagation of nerve impulses between neurons, enabling the brain to send the signals that make us move. In children, diseases affecting this substance are largely genetic and affect a single gene. In adults, the diseases present as inflammatory conditions such as multiple sclerosis. "In the specific case of infant WMD, every type is rare or extremely rare, but if we consider all cases as a single group the incidence is high -- 1 patient for every 1,000 individuals," explains Raúl Estévez, ICREA Acadèmia award winner and a member of the Centre for Biomedical Network Research on Rare Diseases (CIBERER). "In addition," he adds, "in a high percentage of children with myelin disorders the diagnosis is not clear and no real conclusions can be reached."

Thanks to the identification in recent years of abnormal patterns in brain MRIs, researchers have been able to define new diseases. In 1995 experts discovered an autosomal recessive myelin disorder called megalencephalic leukoencephalopathy with subcortical cysts (MLC). In 2001 the gene responsible for 75% of the cases of this disease, MLC1, wa discovered and scientists found that other cases existed that were not caused by mutations of this gene. Of the remaining 25% of patients, two clinical phenotypes were observed: in the first case, the clinical progression, showing progressive degeneration, is the same as observed in the larger group; in the second case, the disease improves or disappears altogether. The common feature in all patients is the presence of macrocephaly, which may be accompanied by learning difficulties and autism.

The study published in The American Journal of Human Genetics takes as its starting point the genetic heterogeneity of the disease and looks for other possible mutations behind its development, combining biochemical and genetic studies. The results show that patients presenting a progressive degeneration of their condition exhibit two mutations in the GlialCAM gene, whose related protein is GlialCAM, while others exhibit only a single mutation in the same gene, which suggests a pattern of autosomal-dominant inheritance. The study, which also describes the biochemical defects observed in the disease, has revealed that mutant GlialCAM can also lead to benign familial macrocephaly and macrocephaly with mental retardation, with or without autism.

"Although we have yet to determine the exact function of GlialCAM, our research has shown that further collaborative multi-disciplinary translational studies will be required to learn more about the causes of these rare diseases and to find new treatments,"

Story Source:

The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by Universidad de Barcelona, via AlphaGalileo.

Journal Reference:

Tania López-Hernández, Margreet C. Ridder, Marisol Montolio, Xavier Capdevila-Nortes, Emiel Polder, Sònia Sirisi, Anna Duarri, Uwe Schulte, Bernd Fakler, Virginia Nunes, Gert C. Scheper, Albert Martínez, Raúl Estévez, Marjo S. van der Knaap. Mutant GlialCAM Causes Megalencephalic Leukoencephalopathy with Subcortical Cysts, Benign Familial Macrocephaly, and Macrocephaly with Retardation and Autism. The American Journal of Human Genetics, 2011; 88 (4): 422 DOI: 10.1016/j.ajhg.2011.02.009

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.


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