Do microbes swim faster or slower in elastic fluids? Research answers long-standing question

ScienceDaily (May 18, 2011) — A biomechanical experiment conducted at the University of Pennsylvania School of Engineering and Applied Science has answered a long-standing theoretical question: Will microorganisms swim faster or slower in elastic fluids? For a prevalent type of swimming, undulation, the answer is "slower."

Paulo Arratia, assistant professor of mechanical engineering and applied mechanics, along with student Xiaoning Shen, conducted the experiment. Their findings were published in the journal Physical Review Letters.

Many animals, microorganisms and cells move by undulation, and they often do so through elastic fluids. From worms aerating wet soil to sperm racing toward an egg, swimming dynamics in elastic fluids is relevant to a number of facets of everyday life; however, decades of research in this area have been almost entirely theoretical or done with computer models. Only a few investigations involved live organisms.

"There have been qualitative observations of sperm cells, for example, where you put sperm in water and watch their tails, then put them in an elastic fluid and see how they swim differently," Arratia said. "But this difference has never been characterized, never put into numbers to quantify exactly how much elasticity affects the way they swim, is it faster or slower and why."

The main obstacle for quantitatively testing these theories with live organisms is developing an elastic fluid in which they can survive, behave normally and in which they can be effectively observed under a microscope.

Arratia and Shen experimented on the nematode C. elegans, building a swimming course for the millimeter-long worms. The researchers filmed them through a microscope while the creatures swam the course in many different liquids with different elasticity but the same viscosity.

Though the two liquid traits, elasticity and viscosity, sound like they are two sides of the same coin, they are actually independent of each other. Viscosity is a liquid's resistance to flowing; elasticity describes its tendency to resume its original shape after it has been deformed. All fluids have some level of viscosity, but certain liquids like saliva or mucus, under certain conditions, can act like a rubber band.

Increased viscosity would slow a swimming organism, but how one would fare with increased elasticity was an open question.

"The theorists had a lot of different predictions," Arratia said. "Some people said elasticity would make things go faster. Others said it would make things go slower. It was all over the map.

"We were the first ones to show that, with this animal, elasticity actually brings the speed and swimming efficiency down."

The reason the nematodes swam slower has to do with how viscosity and elasticity can influence each other.

"In order to make our fluids elastic, we put polymers in them," Arratia said. "DNA, for example, is a polymer. What we use is very similar to DNA, in that if you leave it alone it is coiled. But if you apply a force to it, the DNA or our polymer, will start to unravel.

"With each swimming stroke, the nematode stretches the polymer. And every time the polymers are stretched, the viscosity goes up. And as the viscosity goes up, it's more resistance to move through."

Beyond giving theorists and models a real-world benchmark to work from, Arratia and Shen's experiment opens the door for more live-organism experiments. There are still many un-answered questions relating to swimming dynamics and elasticity.

"We can increase the elasticity and see if there is a mode in which speed goes up again. Once the fluid is strongly elastic, or closer to a solid, we want to see what happens," Arratia said. "Is there a point where it switches from swimming to crawling?"

Arratia and Shen's research was supported by the National Science Foundation.

Story Source:

The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Pennsylvania.

Journal Reference:

X. Shen, P. Arratia. Undulatory Swimming in Viscoelastic Fluids. Physical Review Letters, 2011; 106 (20) DOI: 10.1103/PhysRevLett.106.208101

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

View the original article here

Do microbes swim faster or slower in elastic fluids? Research answers long-standing question

ScienceDaily (May 18, 2011) — A biomechanical experiment conducted at the University of Pennsylvania School of Engineering and Applied Science has answered a long-standing theoretical question: Will microorganisms swim faster or slower in elastic fluids? For a prevalent type of swimming, undulation, the answer is "slower."

Paulo Arratia, assistant professor of mechanical engineering and applied mechanics, along with student Xiaoning Shen, conducted the experiment. Their findings were published in the journal Physical Review Letters.

Many animals, microorganisms and cells move by undulation, and they often do so through elastic fluids. From worms aerating wet soil to sperm racing toward an egg, swimming dynamics in elastic fluids is relevant to a number of facets of everyday life; however, decades of research in this area have been almost entirely theoretical or done with computer models. Only a few investigations involved live organisms.

"There have been qualitative observations of sperm cells, for example, where you put sperm in water and watch their tails, then put them in an elastic fluid and see how they swim differently," Arratia said. "But this difference has never been characterized, never put into numbers to quantify exactly how much elasticity affects the way they swim, is it faster or slower and why."

The main obstacle for quantitatively testing these theories with live organisms is developing an elastic fluid in which they can survive, behave normally and in which they can be effectively observed under a microscope.

Arratia and Shen experimented on the nematode C. elegans, building a swimming course for the millimeter-long worms. The researchers filmed them through a microscope while the creatures swam the course in many different liquids with different elasticity but the same viscosity.

Though the two liquid traits, elasticity and viscosity, sound like they are two sides of the same coin, they are actually independent of each other. Viscosity is a liquid's resistance to flowing; elasticity describes its tendency to resume its original shape after it has been deformed. All fluids have some level of viscosity, but certain liquids like saliva or mucus, under certain conditions, can act like a rubber band.

Increased viscosity would slow a swimming organism, but how one would fare with increased elasticity was an open question.

"The theorists had a lot of different predictions," Arratia said. "Some people said elasticity would make things go faster. Others said it would make things go slower. It was all over the map.

"We were the first ones to show that, with this animal, elasticity actually brings the speed and swimming efficiency down."

The reason the nematodes swam slower has to do with how viscosity and elasticity can influence each other.

"In order to make our fluids elastic, we put polymers in them," Arratia said. "DNA, for example, is a polymer. What we use is very similar to DNA, in that if you leave it alone it is coiled. But if you apply a force to it, the DNA or our polymer, will start to unravel.

"With each swimming stroke, the nematode stretches the polymer. And every time the polymers are stretched, the viscosity goes up. And as the viscosity goes up, it's more resistance to move through."

Beyond giving theorists and models a real-world benchmark to work from, Arratia and Shen's experiment opens the door for more live-organism experiments. There are still many un-answered questions relating to swimming dynamics and elasticity.

"We can increase the elasticity and see if there is a mode in which speed goes up again. Once the fluid is strongly elastic, or closer to a solid, we want to see what happens," Arratia said. "Is there a point where it switches from swimming to crawling?"

Arratia and Shen's research was supported by the National Science Foundation.

Story Source:

The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Pennsylvania.

Journal Reference:

X. Shen, P. Arratia. Undulatory Swimming in Viscoelastic Fluids. Physical Review Letters, 2011; 106 (20) DOI: 10.1103/PhysRevLett.106.208101

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

View the original article here

Fundamental question on how life started solved: Supercomputer calculates carbon nucleus

ScienceDaily (May 10, 2011) — For carbon, the basis of life, to be able to form in the stars, a certain state of the carbon nucleus plays an essential role. In cooperation with US colleagues, physicists from the University of Bonn and Ruhr-Universität Bochum have been able to calculate this legendary carbon nucleus, solving a problem that has kept science guessing for more than 50 years.

The researchers published their results in the coming issue of the scientific journal Physical Review Letters.

"Attempts to calculate the Hoyle state have been unsuccessful since 1954," said Professor Dr. Ulf-G. Meißner (Helmholtz-Institut für Strahlen- und Kernphysik der Universität Bonn). "But now, we have done it!" The Hoyle state is an energy-rich form of the carbon nucleus. It is the mountain pass over which all roads from one valley to the next lead: From the three nuclei of helium gas to the much larger carbon nucleus. This fusion reaction takes place in the hot interior of heavy stars. If the Hoyle state did not exist, only very little carbon or other higher elements such as oxygen, nitrogen and iron could have formed. Without this type of carbon nucleus, life probably also would not have been possible.

The search for the "slave transmitter"

The Hoyle state had been verified by experiments as early as 1954, but calculating it always failed. For this form of carbon consists of only three, very loosely linked helium nuclei -- more of a cloudy diffuse carbon nucleus. And it does not occur individually, only together with other forms of carbon. "This is as if you wanted to analyze a radio signal whose main transmitter and several slave transmitters are interfering with each other," explained Prof. Dr. Evgeny Epelbaum (Institute of Theoretical Physics II at Ruhr-Universität Bochum). The main transmitter is the stable carbon nucleus from which humans -- among others -- are made. "But we are interested in one of the unstable, energy-rich carbon nuclei; so we have to separate the weaker radio transmitter somehow from the dominant signal by means of a noise filter."

What made this possible was a new, improved calculating approach the researchers used that allowed calculating the forces between several nuclear particles more precisely than ever. And in JUGENE, the supercomputer at Forschungszentrum Jülich, a suitable tool was found. It took JUGENE almost a week of calculating. The results matched the experimental data so well that the researchers can be certain that they have indeed calculated the Hoyle state.

More about how the Universe came into existence

"Now we can analyze this exciting and essential form of the carbon nucleus in every detail," explained Prof. Meißner. "We will determine how big it is, and what its structure is. And it also means that we can now take a very close look at the entire chain of how elements are formed."

In future, this may even allow answering philosophical questions using science. For decades, the Hoyle state was a prime example for the theory that natural constants must have precisely their experimentally determined values, and not any different ones, since otherwise we would not be here to observe the Universe (the anthropic principle). "For the Hoyle state this means that it must have exactly the amount of energy it has, or else, we would not exist," said Prof. Meißner. "Now we can calculate whether -- in a changed world with other parameters -- the Hoyle state would indeed have a different energy when comparing the mass of three helium nuclei." If this is so, this would confirm the anthropic principle.

Story Source:

The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Bonn.

Journal Reference:

Evgeny Epelbaum, Hermann Krebs, Dean Lee, Ulf-G. Meißner. Ab Initio Calculation of the Hoyle State. Physical Review Letters, 2011; 106 (19) DOI: 10.1103/PhysRevLett.106.192501

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

View the original article here

Fundamental question on how life started solved: Supercomputer calculates carbon nucleus

ScienceDaily (May 10, 2011) — For carbon, the basis of life, to be able to form in the stars, a certain state of the carbon nucleus plays an essential role. In cooperation with US colleagues, physicists from the University of Bonn and Ruhr-Universität Bochum have been able to calculate this legendary carbon nucleus, solving a problem that has kept science guessing for more than 50 years.

The researchers published their results in the coming issue of the scientific journal Physical Review Letters.

"Attempts to calculate the Hoyle state have been unsuccessful since 1954," said Professor Dr. Ulf-G. Meißner (Helmholtz-Institut für Strahlen- und Kernphysik der Universität Bonn). "But now, we have done it!" The Hoyle state is an energy-rich form of the carbon nucleus. It is the mountain pass over which all roads from one valley to the next lead: From the three nuclei of helium gas to the much larger carbon nucleus. This fusion reaction takes place in the hot interior of heavy stars. If the Hoyle state did not exist, only very little carbon or other higher elements such as oxygen, nitrogen and iron could have formed. Without this type of carbon nucleus, life probably also would not have been possible.

The search for the "slave transmitter"

The Hoyle state had been verified by experiments as early as 1954, but calculating it always failed. For this form of carbon consists of only three, very loosely linked helium nuclei -- more of a cloudy diffuse carbon nucleus. And it does not occur individually, only together with other forms of carbon. "This is as if you wanted to analyze a radio signal whose main transmitter and several slave transmitters are interfering with each other," explained Prof. Dr. Evgeny Epelbaum (Institute of Theoretical Physics II at Ruhr-Universität Bochum). The main transmitter is the stable carbon nucleus from which humans -- among others -- are made. "But we are interested in one of the unstable, energy-rich carbon nuclei; so we have to separate the weaker radio transmitter somehow from the dominant signal by means of a noise filter."

What made this possible was a new, improved calculating approach the researchers used that allowed calculating the forces between several nuclear particles more precisely than ever. And in JUGENE, the supercomputer at Forschungszentrum Jülich, a suitable tool was found. It took JUGENE almost a week of calculating. The results matched the experimental data so well that the researchers can be certain that they have indeed calculated the Hoyle state.

More about how the Universe came into existence

"Now we can analyze this exciting and essential form of the carbon nucleus in every detail," explained Prof. Meißner. "We will determine how big it is, and what its structure is. And it also means that we can now take a very close look at the entire chain of how elements are formed."

In future, this may even allow answering philosophical questions using science. For decades, the Hoyle state was a prime example for the theory that natural constants must have precisely their experimentally determined values, and not any different ones, since otherwise we would not be here to observe the Universe (the anthropic principle). "For the Hoyle state this means that it must have exactly the amount of energy it has, or else, we would not exist," said Prof. Meißner. "Now we can calculate whether -- in a changed world with other parameters -- the Hoyle state would indeed have a different energy when comparing the mass of three helium nuclei." If this is so, this would confirm the anthropic principle.

Story Source:

The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Bonn.

Journal Reference:

Evgeny Epelbaum, Hermann Krebs, Dean Lee, Ulf-G. Meißner. Ab Initio Calculation of the Hoyle State. Physical Review Letters, 2011; 106 (19) DOI: 10.1103/PhysRevLett.106.192501

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

View the original article here